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FOXP3 and Its Cofactors as Targets of Immunotherapies Review

Yasuhiro Nagai,Lian Lam,Mark I. Greene,Hongtao Zhang

Engineering 2019, Volume 5, Issue 1,   Pages 115-121 doi: 10.1016/j.eng.2019.01.001

Abstract: It is well known that FOXP3 forms complexes with several proteins and can be regulated by various post-translational

Keywords： Treg     Forkhead box P3 (FOXP3)     Post-translational modification     Autoimmune     Cancer    

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Using ultrasound to improve the sequential post-synthesis modification method for making mesoporous Y

Rongxin Zhang, Peinan Zhong, Hamidreza Arandiyan, Yanan Guan, Jinmin Liu, Na Wang, Yilai Jiao, Xiaolei Fan

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 2,   Pages 275-287 doi: 10.1007/s11705-019-1905-1

Abstract: Mesoporous Y zeolites were prepared by the sequential chemical dealumination (using chelating agents such as ethylenediaminetetraacetic acid, H EDTA, and citric acid aqueous solutions) and alkaline desilication (using sodium hydroxide, NaOH, aqueous solutions) treatments. Specifically, the ultrasound-assisted alkaline treatment (i.e., ultrasonic treatment) was proposed as the alternative to conventional alkaline treatments which are performed under hydrothermal conditions. In comparison with the hydrothermal alkaline treatment, the ultrasonic treatment showed the comparatively enhanced efficiency (with the reduced treatment time, i.e., 5 min vs. 30 min, all with 0.2 mol·L NaOH at 65°C) in treating the dealuminated Y zeolites for creating mesoporosity. For example, after the treatment of a dealuminated zeolite Y (using 0.1 mol·L H EDTA at 100°C for 6 h), the ultrasonic treatment produced the mesoporous zeolite Y with the specific external surface area ( ) of 160 m ·g and mesopore volume ( ) of 0.22 cm ·g , being slightly higher than that by the conventional method (i.e., = 128 m ·g and = 0.19 cm ·g ). The acidic property and catalytic activity (in catalytic cracking of -octane) of mesoporous Y zeolites obtained by the two methods were comparable. The ultrasonic desilication treatment was found to be generic, also being effective to treat the dealuminated Y zeolites by citric acid. Additionally, the first step of chemical dealumination treatment was crucial to enable the effective creation of mesopores in the parent Y zeolite (with a silicon-to-aluminium ratio, Si/Al= 2.6) regardless of the subsequent alkaline desilication treatment (i.e., ultrasonic or hydrothermal). Therefore, appropriate selection of the condition of the chemical dealumination treatment based on the property of parent zeolites, such as Si/Al ratio and crystallinity, is important for making mesoporous zeolites effectively.

Keywords： zeolite Y     mesoporous zeolite     post-synthesis treatment     ultrasound     chemical dealumination treatment     alkaline    

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improves insulin resistance in overweight/obese subjects with non-alcoholic fatty liver disease: a translational

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 745-759 doi: 10.1007/s11684-021-0880-3

Abstract: This translational approach aimed to explore the effect and underlying mechanism of LGZG in clinicalMethylated DNA immunoprecipitation sequencing and real-time qPCR found that the DNA N6-methyladenine modificationThe underlying mechanism may be related to the regulation of DNA N6-methyladenine modification of PPP1R3A

Keywords： non-alcoholic fatty liver disease     Chinese herbal medicine     randomized controlled trial     DNA N6-methyladenine modification    

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Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals Camouflaging Glycans and Unique Post-Translational Article

Zeyu Sun, Keyi Ren, Xing Zhang, Jinghua Chen, Zhengyi Jiang, Jing Jiang, Feiyang Ji, Xiaoxi Ouyang, Lanjuan Li

Engineering 2021, Volume 7, Issue 10,   Pages 1441-1451 doi: 10.1016/j.eng.2020.07.014

Abstract: Additional post-translational modification (PTM) was identified, including multiple methylated sites

Keywords： N-glycosylation     COVID-19     Spike protein     hACE2     Structure    

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Upgrading pyrolytic carbon-blacks (CBp) from end-of-life tires: Characteristics and modification methodologies

Jiaxue Yu, Junqing Xu, Zhenchen Li, Wenzhi He, Juwen Huang, Junshi Xu, Guangming Li

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 2, doi: 10.1007/s11783-019-1198-0

Abstract: Modification methodologies of upgrading CBp from ELTs were reviewed.However, due to the lack of systematic characteristic analysis and modification methods, poor qualityIn this review, we have summarized the state-of-the-art characteristics and modification methodologiesunderstand the surface microstructures and physiochemical properties of CBp for the foundation for modificationBy virtue of the proper selection of modification methods and modifying agents, the new generation of

Keywords： Pyrolysis carbon-blacks     CBp     Post-pyrolysis     Demineralization     Surface modification    

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Error analysis and optimization of a 3-degree of freedom translational Parallel Kinematic Machine

S. SHANKAR GANESH,A. B. KOTESWARA RAO

Frontiers of Mechanical Engineering 2014, Volume 9, Issue 2,   Pages 120-129 doi: 10.1007/s11465-014-0300-3

Abstract:

In this paper, error modeling and analysis of a typical 3-degree of freedom translational ParallelThis mechanism provides translational motion along the Cartesian X-, Y- and 

Keywords： translational Parallel Kinematic Machine     error modeling     global error transformation index    

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Numerical analysis of hydrodynamic process of circular-translational-moving polishing (CTMP)

ZHAI Wenjie, LIU Changxiong, LIANG Yingchun

Frontiers of Mechanical Engineering 2008, Volume 3, Issue 4,   Pages 441-448 doi: 10.1007/s11465-008-0074-6

Abstract: a wafer along a circular path without rotation, we developed a polishing technique called circular-translational-moving

Keywords： numerical analysis     practical CTMP     circular-translational-moving polishing     CTMP     different    

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Bone metastasis of hepatocellular carcinoma: facts and hopes from clinical and translational perspectives

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 551-573 doi: 10.1007/s11684-022-0928-z

Abstract: We also present the advances in the pathological and molecular mechanisms of HCC BM to shed light on translational

Keywords： HCC     bone     osteotropism     clinical     basic researches     advances    

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Stiffness of a 3-degree of freedom translational parallel kinematic machine

S. SHANKAR GANESH,A.B. KOTESWARA RAO

Frontiers of Mechanical Engineering 2014, Volume 9, Issue 3,   Pages 233-241 doi: 10.1007/s11465-014-0312-z

Abstract:

In this paper, a typical 3-degree of freedom (3-DOF) translational parallel kinematic machineUsing the stiffness modeling the variations of minimum and maximum translational stiffness in the workspace

Keywords： 3-DOF translational PKM     inverse kinematics     stiffness modeling     translational stiffness    

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Conceptual design of compliant translational joints for high-precision applications

Guangbo HAO,Haiyang LI,Xiuyun HE,Xianwen KONG

Frontiers of Mechanical Engineering 2014, Volume 9, Issue 4,   Pages 331-343 doi: 10.1007/s11465-014-0321-y

Abstract:

Compliant translational joints (CTJs) have been extensively used in precision engineering and microelectromechanical

Keywords： compliant mechanisms     translational joints     conceptual design     parallelogram     straight-line motion     combination    

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Dendritic cell vaccines in cancer immunotherapy: from biology to translational medicine

Hongmei Xu, Xuetao Cao

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 323-332 doi: 10.1007/s11684-011-0172-4

Abstract:
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Design and analysis of partially decoupled translational parallel mechanisms with single-loop structures

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 3, doi: 10.1007/s11465-022-0695-1

Abstract: This study presents a family of novel translational parallel mechanisms (TPMs) with single-loop topologicalThe workspace of the 3-CRR (C denotes the cylindrical joint and R denotes the revolute joint) translational

Keywords： translational parallel mechanism     single loop     multiple driving system     workspace analysis     singularity    

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Overcoming the challenges of conducting translational research in cell therapy

Sowmya Viswanathan, Armand Keating

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 333-335 doi: 10.1007/s11684-011-0166-2

Abstract: medical needs but despite its considerable impetus, faces numerous challenges including support for translationalexamine the challenges confronting cell therapy research including the limited funding available for translational

Keywords： stem cells     clinical trials     funding     animal models     standardization     common definitions    

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Sustainable functionalization and modification of materials via multicomponent reactions in water

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 9,   Pages 1318-1344 doi: 10.1007/s11705-022-2150-6

Abstract: ground providing essential design criteria to develop advanced tools for efficient functionalization and modificationTo date, there is no exclusive review to report the sustainable functionalization and modification ofkinds of multicomponent reactions in water and aqueous media as green methods for functionalization and modification

Keywords： materials     multicomponent reactions     modification     functionalization     water    

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Acupuncture-related techniques for the treatment of opiate addiction: a case of translational medicine

Jisheng Han, Cailian Cui, Liuzhen Wu

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 141-150 doi: 10.1007/s11684-011-0136-8

Abstract: use of acupuncture-related technique for the treatment of opiate addiction from the perspective of translational

Keywords： morphine     dependence     withdrawal     addiction     dynorphins     acupuncture     electroacupuncture     transcutaneous electrical acupoint stimulation (TEAS)     enkephalins     endorphins    

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Title Author Date Type Operation

FOXP3 and Its Cofactors as Targets of Immunotherapies

Yasuhiro Nagai,Lian Lam,Mark I. Greene,Hongtao Zhang

Journal Article

Using ultrasound to improve the sequential post-synthesis modification method for making mesoporous Y

Rongxin Zhang, Peinan Zhong, Hamidreza Arandiyan, Yanan Guan, Jinmin Liu, Na Wang, Yilai Jiao, Xiaolei Fan

Journal Article

improves insulin resistance in overweight/obese subjects with non-alcoholic fatty liver disease: a translational

Journal Article

Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals Camouflaging Glycans and Unique Post-Translational

Zeyu Sun, Keyi Ren, Xing Zhang, Jinghua Chen, Zhengyi Jiang, Jing Jiang, Feiyang Ji, Xiaoxi Ouyang, Lanjuan Li

Journal Article

Upgrading pyrolytic carbon-blacks (CBp) from end-of-life tires: Characteristics and modification methodologies

Jiaxue Yu, Junqing Xu, Zhenchen Li, Wenzhi He, Juwen Huang, Junshi Xu, Guangming Li

Journal Article

Error analysis and optimization of a 3-degree of freedom translational Parallel Kinematic Machine

S. SHANKAR GANESH,A. B. KOTESWARA RAO

Journal Article

Numerical analysis of hydrodynamic process of circular-translational-moving polishing (CTMP)

ZHAI Wenjie, LIU Changxiong, LIANG Yingchun

Journal Article

Bone metastasis of hepatocellular carcinoma: facts and hopes from clinical and translational perspectives

Journal Article

Stiffness of a 3-degree of freedom translational parallel kinematic machine

S. SHANKAR GANESH,A.B. KOTESWARA RAO

Journal Article

Conceptual design of compliant translational joints for high-precision applications

Guangbo HAO,Haiyang LI,Xiuyun HE,Xianwen KONG

Journal Article

Dendritic cell vaccines in cancer immunotherapy: from biology to translational medicine

Hongmei Xu, Xuetao Cao

Journal Article

Design and analysis of partially decoupled translational parallel mechanisms with single-loop structures

Journal Article

Overcoming the challenges of conducting translational research in cell therapy

Sowmya Viswanathan, Armand Keating

Journal Article

Sustainable functionalization and modification of materials via multicomponent reactions in water

Journal Article

Acupuncture-related techniques for the treatment of opiate addiction: a case of translational medicine

Jisheng Han, Cailian Cui, Liuzhen Wu

Journal Article